Coordinated angiogenesis, lymphangiogenesis and neurogenesis is crucial for healthy, healing skin. As the hair follicle remodels during cycling, the dynamic physical association of skin appendages and the cell-signaling processes can reveal important information regarding hair growth. We examine the interactive triad of nerve, vessels and lymphatic networks of the hair follicle to understand how the perifollicular unit responds and adapts to endogenous and environmental changes. I will discuss our work on both the human and murine hair cycle with focus on alopecia areata and androgenetic alopecia. I will present recent work on skin cancer with respect to 1) development of a new sun screen product
and 2) a mechanism of UV-induced carcinogenesis by capsaicin, the active ingredient in chili peppers.
Bio: Dr. Ericson joined the University of Minnesota Department of Dermatology in 1996 as part of the Clinical Research Division team. She is director of the research laboratory in Dermatology located in Diehl Hall and leads the Basic Science Fridays resident lecture series.
Her interests lie in imaging with special emphasis on single- and multi-photon laser scanning confocal microscopy. Her expertise in imaging has led to fruitful collaborations with other investigators outside the Department of Dermatology in the fields of infectious diseases, oncology, neuroscience, rheumatology, engineering, dentistry, and orthopedics.
Current research activities include cancer pain in a murine model, mechanisms of hair growth, tumor/T-cell interactions, mechanism of mammalian/tick infection, and second harmonic imaging of collagen.